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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 927680생성일: 2026년 10월 25일

6-((Tetrahydro-2H-pyran-4-yl)methoxy)-5-(trifluoromethyl)picolinic acid → 2-Ethyl-2-{[6-(tetrahydro-pyran-4-ylmethoxy)-5-trifluoromethyl-pyridine-2-carbonyl]-amino}-butyric acid methyl ester

https://huagongshe.com/reaction/927680

반응식

참여 물질

역할이름HCID투입량
반응물6-((Tetrahydro-2H-pyran-4-yl)methoxy)-5-(trifluoromethyl)picolinic acidHCID 71087388—
반응물Methyl 2-amino-2-ethylbutanoate hydrochlorideHCID 75488114—
생성물2-Ethyl-2-{[6-(tetrahydro-pyran-4-ylmethoxy)-5-trifluoromethyl-pyridine-2-carbonyl]-amino}-butyric acid methyl esterHCID 71087415—

반응 단계

The title compound was synthesized in analogy to Example 1, using 6-((tetrahydro-2H-pyran-4-yl)methoxy)-5-(trifluoromethyl)picolinic acid (Example 230 b) and methyl 2-amino-2-ethylbutanoate hydrochloride (CAN 92398-54-4) as starting materials, MS (EI): m/e=433.5 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09290451B2
출처 데이터셋uspto-grants-2016_03
ORD IDord-a93922aa8bb64dbca8454aad24eb3edc
출처 메모uspto-grants-2016_03