반응식
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:15]([OH:17])=O)=[N:6][C:7]=1[O:8][CH2:9][C:10]1([CH3:14])[CH2:13][O:12][CH2:11]1.Cl.[S:19]1[CH:23]=[CH:22][N:21]=[C:20]1[C:24]1([NH2:28])[CH2:27][O:26][CH2:25]1>>[S:19]1[CH:23]=[CH:22][N:21]=[C:20]1[C:24]1([NH:28][C:15]([C:5]2[CH:4]=[CH:3][C:2]([Br:1])=[C:7]([O:8][CH2:9][C:10]3([CH3:14])[CH2:11][O:12][CH2:13]3)[N:6]=2)=[O:17])[CH2:27][O:26][CH2:25]1참가 물질
3
실험 절차
The title compound was synthesized in analogy to Example 280c, using 5-bromo-6-(3-methyl-oxetan-3-ylmethoxy)-pyridine-2-carboxylic acid (Example 280b) and 3-(thiazol-2-yl)oxetan-3-amine hydrochloride (Example 281b) as starting materials, MS (EI): m/e=440.4 [M+H]+.
출처 및 근거
- ORD 기록
- ord-d9bc7024a7bd4e8687860b790a21e1eb
- 출처 데이터셋
- uspto-grants-2016_03
- 특허 번호
- US09290451B2
연결된 노트
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