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(S)-1-ethyl-3-(3-fluorobenzyl)pyrrolidine → 2-((S)-1-ethylpyrrolidin-3-ylmethyl)-4-fluorobenzenesulfonyl chloride

HRID 927994
노트
인쇄 미리보기

반응식

HRID 927994 반응식
[CH2:1]([N:3]1[CH2:7][CH2:6][C@@H:5]([CH2:8][C:9]2[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:10]=2[S:16]([Cl:19])(=[O:18])=[O:17])[CH2:4]1)[CH3:2].C(N1CC[C@H](CC2C=CC=C(F)C=2)C1)C>>[CH2:1]([N:3]1[CH2:7][CH2:6][C@H:5]([CH2:8][C:9]2[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:10]=2[S:16]([Cl:19])(=[O:17])=[O:18])[CH2:4]1)[CH3:2]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

3

반응물 2

HCID 70984055(S)-1-ethyl-3-(3-fluorobenzyl)pyrrolidine2회HCID 867133192-((R)-1-ethylpyrrolidin-3-ylmethyl)-4-fluorobenzenesulfonyl chloride

생성물 1

HCID 867133272-((S)-1-ethylpyrrolidin-3-ylmethyl)-4-fluorobenzenesulfonyl chloride

실험 절차

Prepared by proceeding in a similar manner to Intermediate 96, starting from (S)-1-ethyl-3-(3-fluorobenzyl)pyrrolidine (Intermediate 115).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-f60ec38d844243d1b145934029f0b8bb
출처 데이터셋
uspto-grants-2016_03
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US09290472B2

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