(R)-1-ethyl-3-(3-fluorobenzyl)pyrrolidine → (S)-1-ethyl-3-(3-fluorobenzyl)pyrrolidine

HRID 927995노트

반응식

HRID 927995 반응식
[CH2:1]([N:3]1[CH2:7][CH2:6][C@@H:5]([CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([F:15])[CH:10]=2)[CH2:4]1)[CH3:2].FC1C=C(C=CC=1)C[C@H]1CCNC1>>[CH2:1]([N:3]1[CH2:7][CH2:6][C@H:5]([CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([F:15])[CH:10]=2)[CH2:4]1)[CH3:2]

참가 물질

3

반응물 2

HCID 70983712(R)-1-ethyl-3-(3-fluorobenzyl)pyrrolidineHCID 863184953-(S)-(3-Fluorobenzyl)-pyrrolidine2회

생성물 1

HCID 70984055(S)-1-ethyl-3-(3-fluorobenzyl)pyrrolidine

실험 절차

Prepared by proceeding in a similar manner to Intermediate 97 starting with 3-(S)-(3-fluoro-benzyl)pyrrolidine (Intermediate 116).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-c851e24399cb4debbbe36ea179b849d9
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290472B2

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