tert-butyl (S)-3-(3-fluorobenzyl)-pyrrolidine-1-carboxylate → 3-(S)-(3-Fluorobenzyl)-pyrrolidine

HRID 927996노트

반응식

HRID 927996 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:11]=[CH:12][CH:13]=1)[CH2:5][C@@H:6]1[CH2:10][CH2:9][NH:8][CH2:7]1.FC1C=C(C=CC=1)C[C@H]1CCN(C(OC(C)(C)C)=O)C1>>[F:1][C:2]1[CH:3]=[C:4]([CH:11]=[CH:12][CH:13]=1)[CH2:5][C@H:6]1[CH2:10][CH2:9][NH:8][CH2:7]1

참가 물질

3

반응물 2

HCID 71006981tert-butyl (S)-3-(3-fluorobenzyl)-pyrrolidine-1-carboxylate2회HCID 863184933-(R)-(3-fluorobenzyl)pyrrolidine

생성물 1

HCID 863184953-(S)-(3-Fluorobenzyl)-pyrrolidine

실험 절차

Prepared by proceeding in a similar manner to Intermediate 98 starting with tert-butyl (S)-3-(3-fluorobenzyl)-pyrrolidine-1-carboxylate (intermediate 117).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-911a2e5c12ff4e7ca100afba92cb2103
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290472B2

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