N-((S)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride → N-((R)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride

HRID 928008노트

반응식

HRID 928008 반응식
[ClH:1].Cl.[CH2:3]([N:5]1[CH2:9][CH2:8][C@H:7]([NH:10][CH3:11])[CH2:6]1)[CH3:4].C(N1CC[C@@H](N(C)C(=O)OCC2C=CC=CC=2)C1)C>>[ClH:1].[ClH:1].[CH2:3]([N:5]1[CH2:9][CH2:8][C@@H:7]([NH:10][CH3:11])[CH2:6]1)[CH3:4]

참가 물질

3

반응물 2

HCID 86713333N-((S)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochlorideHCID 86713337benzyl N-((R)-1-ethylpyrrolidin-3-yl)-N-methylcarbamate2회

생성물 1

HCID 86713336N-((R)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride

실험 절차

Prepared by proceeding in a similar manner to Intermediate 127, starting from benzyl N—((R)-1-ethylpyrrolidin-3-yl)-N-methylcarbamate (Intermediate 133) as a light coloured viscous oil, which was used without further characterization.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-74d3b56d67514f0fb685f0929e5dddcd
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290472B2

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