tert-butyl (2R)-2-(cyanomethyl)pyrrolidine-1-carboxylate → (R)-2-(Pyrrolidin-2-yl)acetonitrile hydrochloride

HRID 928018노트

반응식

HRID 928018 반응식
[ClH:1].[NH:2]1[CH2:6][CH2:5][CH2:4][C@H:3]1[CH2:7][C:8]#[N:9].C(C[C@H]1CCCN1C(OC(C)(C)C)=O)#N>>[ClH:1].[NH:2]1[CH2:6][CH2:5][CH2:4][C@@H:3]1[CH2:7][C:8]#[N:9]

참가 물질

3

반응물 2

HCID 10727173tert-butyl (2R)-2-(cyanomethyl)pyrrolidine-1-carboxylate2회HCID 86713338(S)-2-(Pyrrolidin-2-yl)acetonitrile hydrochloride

생성물 1

HCID 86713341(R)-2-(Pyrrolidin-2-yl)acetonitrile hydrochloride

실험 절차

Prepared by proceeding in a similar manner to Intermediate 138, starting from tert-butyl (R)-2-cyanomethylpyrrolidine-1-carboxylate (Intermediate 144) and used without further characterisation.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-ba1b5a73778c47a1b85026918b8ff7f3
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290472B2

반응 노트

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