1-ethyl-L-Proline → (2R)-1-ethylpyrrolidine-2-carboxylic acid

HRID 928022노트

반응식

HRID 928022 반응식
[CH2:1]([N:3]1[CH2:7][CH2:6][CH2:5][C@H:4]1[C:8]([OH:10])=[O:9])[CH3:2].C(N1CCC[C@@H]1C(OC(C)(C)C)=O)C>>[CH2:1]([N:3]1[CH2:7][CH2:6][CH2:5][C@@H:4]1[C:8]([OH:10])=[O:9])[CH3:2]

참가 물질

3

반응물 2

HCID 283547181-ethyl-L-ProlineHCID 80709654tert-butyl (R)-1-ethylpyrrolidine-2-carboxylate2회

생성물 1

HCID 28354716(2R)-1-ethylpyrrolidine-2-carboxylic acid

실험 절차

Prepared by proceeding in a similar manner to Intermediate 106, starting from tert-butyl (R)-1-ethylpyrrolidine-2-carboxylate (Intermediate 148) as a solid.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-136c981539c64c64bb6a51caf598ea63
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290472B2

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