benzyl (S)-1-ethylpyrrolidine-3-carboxylate → benzyl (R)-1-ethylpyrrolidine-3-carboxylate

HRID 928058노트

반응식

HRID 928058 반응식
[CH2:1]([N:3]1[CH2:7][CH2:6][C@H:5]([C:8]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:9])[CH2:4]1)[CH3:2].FC(F)(F)C(O)=O.N1CC[C@@H](C(OCC2C=CC=CC=2)=O)C1>>[CH2:1]([N:3]1[CH2:7][CH2:6][C@@H:5]([C:8]([O:10][CH2:11][C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)=[O:9])[CH2:4]1)[CH3:2]

참가 물질

3

반응물 2

HCID 71006998benzyl (S)-1-ethylpyrrolidine-3-carboxylateHCID 86713358(R)-Benzyl pyrrolidine-3-carboxylate trifluoroacetic acid salt2회

생성물 1

HCID 86713357benzyl (R)-1-ethylpyrrolidine-3-carboxylate

실험 절차

Prepared by proceeding in a simialr manner to Intermediate 190, starting from benzyl (R)-pyrrolidine-3-carboxylate trifluoroacetic acid salt (Intermediate 198).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-4a9bcedec3b54b068c5ff616ebea2142
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290472B2

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