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(R)-1-ethyl-2-[2-(3-fluorophenyl)ethyl]pyrrolidine → 2-[2-((R)-1-Ethylpyrrolidin-2-yl)ethyl]-4-fluorobenzenesulfonyl chloride

HRID 928083
노트
인쇄 미리보기

반응식

HRID 928083 반응식
[CH2:1]([N:3]1[CH2:7][CH2:6][C@@H:5]([CH2:8][C:9]2[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:10]=2[S:16]([Cl:19])(=[O:18])=[O:17])[CH2:4]1)[CH3:2].[CH2:20](N1CCC[C@H]1CCC1C=CC=C(F)C=1)C>>[CH2:1]([N:3]1[CH2:7][CH2:6][CH2:20][C@H:4]1[CH2:5][CH2:8][C:9]1[CH:14]=[C:13]([F:15])[CH:12]=[CH:11][C:10]=1[S:16]([Cl:19])(=[O:17])=[O:18])[CH3:2]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

3

반응물 2

HCID 71007002(R)-1-ethyl-2-[2-(3-fluorophenyl)ethyl]pyrrolidine2회HCID 867133192-((R)-1-ethylpyrrolidin-3-ylmethyl)-4-fluorobenzenesulfonyl chloride

생성물 1

HCID 867133762-[2-((R)-1-Ethylpyrrolidin-2-yl)ethyl]-4-fluorobenzenesulfonyl chloride

실험 절차

Prepared by proceeding in a similar manner to intermediate 96, starting from (R)-1-ethyl-2-[2-(3-fluorophenyl)ethyl]pyrrolidine (intermediate 231).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-2384805ea0a94ce289ee5a09b3d0a3c9
출처 데이터셋
uspto-grants-2016_03
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US09290472B2

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