Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Hydroxysuccinimide S-acetylthioacetate → HCID 86720322, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Hydroxysuccinimide S-acetylthioacetate | HCID 127532 | — |
| 반응물 | Acalabrutinib Intermediate | HCID 71226368 | — |
| 생성물 | HCID 86720322 | HCID 86720322 | 31.8% |
반응 단계
This compound was prepared, in an analogous manner as described in Example 1, from the compound described in intermediate 2b and 2,5-dioxopyrrolidin-1-yl 2-(acetylthio)acetate, to afford the title compound (12.3 mg, 31.8%). Data: UPLC (C) R: 1.51 min; m/z 516.3 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09290504B2 |
| 출처 데이터셋 | uspto-grants-2016_03 |
| ORD ID | ord-bb823ed57013428c84233add4cbfec05 |
| 출처 메모 | uspto-grants-2016_03 |