Benzaldehyde → HCID 178489586, 화합물

HRID 928881노트

반응식

HRID 928881 반응식
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:9][O:10][C:11]1[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=1[NH2:13].O>C1(C)C=CC=CC=1>[CH:1](=[N:13]/[C:12]1[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=1[O:10][CH3:9])\[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 240BenzaldehydeHCID 962WaterHCID 70002-Methoxyaniline

생성물 1

HCID 178489586HCID 178489586, 화합물수율 99.8%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

To benzaldehyde (26.1 g, 25.0 mL, 0.246 mol, 1.21 equiv) in toluene (100 mL) was added 2-methoxyaniline (25.1 g, 23.0 mL, 0.204 mol, 1.00 equiv). The reaction mixture was heated to reflux with azeotropic removal of water with a Dean-Stark trap for 12 h. The reaction mixture was concentrated and dried under high vacuum to afford (E)-N-benzylidene-2-methoxyaniline as a yellow oil (43.0 g, >99% yield).

후처리

  1. temperatureThe reaction mixture was heated
  2. concentrationThe reaction mixture was concentrated
  3. customdried under high vacuum

출처 및 근거

ORD 기록
ord-fe52b3cebe0e4e1ba2ed635f2dd3637d
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290591B2

반응 노트

불러오는 중…