HCID 90042500, 화합물 → (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diamine
반응식
[N:1]([C@@H:4]1[CH2:8][O:7][C@@H:6]2[C@@H:9]([N:12]=[N+]=[N-])[CH2:10][O:11][C@H:5]12)=[N+]=[N-]>CO.[Pd]>[O:7]1[CH2:8][C@@H:4]([NH2:1])[C@H:5]2[O:11][CH2:10][C@H:9]([NH2:12])[C@@H:6]12참가 물질
4
실험 절차
A mixture of (3R,3aR,6S,6aR)-3,6-diazidohexahydrofuro[3,2-b]furan (2.5 g, 12.74 mmol) and 5% palladium on active carbon (0.25 g) in methanol (300 mL) was hydrogenated under 40 psi in an autoclave overnight. The catalyst was removed by filtration and the solvent was evaporated to give the desired product, which was used in the next step without further purification.
후처리
- customThe catalyst was removed by filtration
- customthe solvent was evaporated
출처 및 근거
- ORD 기록
- ord-503827e261c94d06bc10ce1c6d339b2e
- 출처 데이터셋
- uspto-grants-2016_03
- 특허 번호
- US09290517B2
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