Thionyl Chloride → 2-(4-ethoxyphenyl)acetyl Chloride

HRID 929736

반응식

[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([OH:13])=O)=[CH:6][CH:5]=1)[CH3:2].S(Cl)([Cl:16])=O>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([Cl:16])=[O:13])=[CH:6][CH:5]=1)[CH3:2]

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 78631Benzeneacetic acid, 4-ethoxy-

생성물 1

HCID 116297822-(4-ethoxyphenyl)acetyl Chloride

반응 조건

온도: 70 °C

실험 절차

4-Ethoxyphenylacetic acid (0.5 g, 2.8 mmol) was transferred to a 7 ml vial and dissolved in thionylchloride (3 ml). The reaction mixture was shaken at 70° C. for 21/2 hours. Thionylchloride was evaporated off and the resulting product was used unpurified.

후처리

customThionylchloride was evaporated off

출처 및 근거

ORD 기록: ord-06de92c37c804f80ad9dfd09f1479dee
출처 데이터셋: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09296694B2

연결된 노트

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