3-Hydrazinylpyridine hydrochloride → HCID 89602438, 화합물

HRID 930001노트

반응식

HRID 930001 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=CN=3)[N:12]=[C:11]([C:20]([OH:22])=[O:21])[CH:10]=2)[CH:5]=[C:6]([F:8])[CH:7]=1.Cl.[N:24]1C=CC=C(NN)[CH:25]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:25]=[N:24][CH:17]=[CH:18][CH:19]=3)[N:12]=[C:11]([C:20]([OH:22])=[O:21])[CH:10]=2)[CH:5]=[C:6]([F:8])[CH:7]=1

참가 물질

3

반응물 2

HCID 231434543-Hydrazinylpyridine hydrochlorideHCID 896025755-(3-Chloro-5-fluorophenyl)-1-(pyridin-2-yl)-1H-pyrazole-3-carboxylic acid

생성물 1

HCID 89602438HCID 89602438, 화합물

실험 절차

807 mg (2.90 mmol) of the compound of Example 1A is reacted analogously to the synthesis of the compound of Example 20A with 464 mg (3.19 mmol) of 3-pyridylhydrazine hydrochloride. After hydrolysis, 353 mg (38% of theory) of the title compound is obtained.

출처 및 근거

ORD 기록
ord-58ea4d4ef55f425e82b68b610a9566a8
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09296720B2

반응 노트

불러오는 중…