5-Chloro-3-methoxy-pyridine-2-carboxylic acid → 4-Chloro-7-methoxypyrido(3,2-d)pyrimidine

HRID 930453노트

반응식

HRID 930453 반응식
[Cl:1]C1C=C(OC)C(C(O)=O)=NC=1.[CH3:13][O:14][C:15]1[CH:24]=[N:23][C:22]2[C:21](=O)[N:20]=[CH:19][NH:18][C:17]=2[CH:16]=1>>[Cl:1][C:21]1[C:22]2[N:23]=[CH:24][C:15]([O:14][CH3:13])=[CH:16][C:17]=2[N:18]=[CH:19][N:20]=1

참가 물질

3

반응물 2

HCID 840704685-Chloro-3-methoxy-pyridine-2-carboxylic acidHCID 178493687HCID 178493687, 화합물

생성물 1

HCID 867159014-Chloro-7-methoxypyrido(3,2-d)pyrimidine

실험 절차

Using an analogous reaction to that described for Intermediate 14, step 3, 7-methoxypyrido[3,2-d]pyrimidin-4(1H)-one was converted to the title compound. LC/MS (ESI+) m/z=196 (M+H).

후처리

  1. customan analogous reaction to

출처 및 근거

ORD 기록
ord-68cdb2d555de43d191cd428075329bde
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09296734B2

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