m-Chloroperbenzoic acid → HCID 89853680, 화합물

HRID 931129노트

반응식

HRID 931129 반응식
ClC1C=C(C=CC=1)C(OO)=[O:6].[N:12]1[CH:17]=[CH:16][CH:15]=[C:14]([C:18]2([C:21]([O:23]CC)=[O:22])[CH2:20][CH2:19]2)[CH:13]=1>ClCCl>[C:21]([C:18]1([C:14]2[CH:13]=[N+:12]([O-:6])[CH:17]=[CH:16][CH:15]=2)[CH2:20][CH2:19]1)([OH:23])=[O:22]

참가 물질

4

반응물 2

HCID 70297m-Chloroperbenzoic acidHCID 21054369Ethyl 1-(pyridin-3-yl)cyclopropane-1-carboxylate

생성물 1

HCID 89853680HCID 89853680, 화합물수율 58.1%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

70% meta-Chloroperoxybenzoic acid (1.2 g, 4.9 mmol) was added to a solution of ethyl 1-(pyridin-3-yl)cyclopropanecarboxylate (400 mg, 2.4 mmol) in dichloromethane (5 mL) at room temperature and stirred for 16 h. The resulting precipitate was filtered and triturated with dichloromethane to afford the title compound (250 mg).

후처리

  1. filtrationThe resulting precipitate was filtered
  2. customtriturated with dichloromethane

출처 및 근거

ORD 기록
ord-296c5dbf1f554ca6914be0b18e3bee67
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09296745B2

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