1-Isopropylhydrazine → 2-(propan-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine

HRID 931361노트

반응식

HRID 931361 반응식
CN(/[CH:4]=[C:5]1\[CH2:6][N:7](C(OC(C)(C)C)=O)[CH2:8][CH2:9][C:10]\1=O)C.[CH3:19][CH:20]([NH:22][NH2:23])[CH3:21]>>[CH3:19][CH:20]([N:22]1[CH:4]=[C:5]2[CH2:6][NH:7][CH2:8][CH2:9][C:10]2=[N:23]1)[CH3:21]

참가 물질

3

반응물 2

HCID 527891-IsopropylhydrazineHCID 10610967tert-butyl (3E)-3-[(dimethylamino)methylidene]-4-oxopiperidine-1-carboxylate

생성물 1

HCID 838631362-(propan-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine

실험 절차

tert-Butyl (3E)-3-[(dimethylamino)methylidene]-4-oxopiperidine-1-carboxylate was condensed with propan-2-ylhydrazine; removal of the protecting group provided 2-(propan-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine.

후처리

  1. customremoval of the protecting group

출처 및 근거

ORD 기록
ord-84b3a0b4baa6401c8b1725dfed1ecd0f
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09296761B2

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