5-(4-Chlorophenyl)-2,7-dimethylquinolin-6-ol → 5-(4-Chlorophenyl)-2,7-dimethylquinolin-6-yl trifluoromethanesulfonate

HRID 931709노트

반응식

HRID 931709 반응식
[F:1][C:2]([F:27])([F:26])[S:3]([O:6][C:7]1[C:8]([C:19]2[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=2)=[C:9]2[C:14](=[CH:15][C:16]=1Cl)[N:13]=[C:12]([CH3:18])[CH:11]=[CH:10]2)(=[O:5])=[O:4].Cl[C:29]1C=CC(C2C(O)=C(C)C=C3C=2C=CC(C)=N3)=CC=1>>[F:1][C:2]([F:27])([F:26])[S:3]([O:6][C:7]1[C:8]([C:19]2[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=2)=[C:9]2[C:14](=[CH:15][C:16]=1[CH3:29])[N:13]=[C:12]([CH3:18])[CH:11]=[CH:10]2)(=[O:5])=[O:4]

참가 물질

3

반응물 2

HCID 666320955-(4-Chlorophenyl)-2,7-dimethylquinolin-6-olHCID 866919727-Chloro-5-(4-chlorophenyl)-2-methylquinolin-6-yl trifluoromethanesulfonate

생성물 1

HCID 866919745-(4-Chlorophenyl)-2,7-dimethylquinolin-6-yl trifluoromethanesulfonate

실험 절차

Compound 2E was prepared following the procedure used to prepare compound 1F of Example 1, except that 5-(4-chlorophenyl)-2,7-dimethylquinolin-6-ol (2D) was used instead of compound 1E. LCMS-ESI+ (m/z): 416.0, 418.0 (M+H)+.

출처 및 근거

ORD 기록
ord-a13d5e05430e4f9baa8b22baf2105c63
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09296758B2

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