7-Methylquinolin-6-ol → 5-Bromo-6-hydroxy-7-methyl-quinoline

반응식

[Br:1][C:2]1[C:11]([OH:12])=[C:10](Cl)[CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](C)=[N:7]2.[CH3:15]C1C=C2C(C=CC=N2)=CC=1O>>[Br:1][C:2]1[C:11]([OH:12])=[C:10]([CH3:15])[CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2

참가 물질

반응물 2

HCID 128389567-Methylquinolin-6-ol

HCID 666313995-Bromo-7-chloro-2-methylquinolin-6-ol

생성물 1

HCID 230783095-Bromo-6-hydroxy-7-methyl-quinoline

실험 절차

Compound 3D was prepared following the procedure used to prepare compound 1D of Example 1, except that 7-methylquinolin-6-ol (3C) was used instead of compound 1C. LCMS-ESI+ (m/z): 238.1, 240.1 (M+H)+.

출처 및 근거

ORD 기록: ord-a82bd784676e469995b92ed214ef52b0
출처 데이터셋: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09296758B2

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