7-Chloro-5-(4-chlorophenyl)-2-methylquinolin-6-yl trifluoromethanesulfonate → 8-(4-Chlorophenyl)-6-methylquinolin-7-yl trifluoromethanesulfonate
반응식
[F:1][C:2]([F:27])([F:26])[S:3](OC1C(C2C=CC(Cl)=CC=2)=C2C(=CC=1Cl)N=C(C)C=C2)(=[O:5])=[O:4].[Cl:28][C:29]1[CH:34]=[CH:33][C:32]([C:35]2[C:36]([OH:46])=[C:37]([CH3:45])[CH:38]=[C:39]3[C:44]=2[N:43]=[CH:42][CH:41]=[CH:40]3)=[CH:31][CH:30]=1>>[F:1][C:2]([F:27])([F:26])[S:3]([O:46][C:36]1[C:35]([C:32]2[CH:31]=[CH:30][C:29]([Cl:28])=[CH:34][CH:33]=2)=[C:44]2[C:39]([CH:40]=[CH:41][CH:42]=[N:43]2)=[CH:38][C:37]=1[CH3:45])(=[O:5])=[O:4]참가 물질
3
실험 절차
Compound 4D was prepared following the procedure used to prepare compound 1F of example 1, except that 8-(4-chloro-phenyl)-6-methylquinolin-7-ol (4C) was used instead of compound 1E. LCMS-ESI+ (m/z): 402.0, 403.9 (M+H)+.
출처 및 근거
- ORD 기록
- ord-fd3552149e984b2d85d68101bed92068
- 출처 데이터셋
- uspto-grants-2016_03
- 특허 번호
- US09296758B2
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