6-Methyl-2-pyridinecarboxaldehyde → 1-(6-Methylpyridin-2-yl)propan-1-ol

반응식

[CH3:1][C:2]1[N:7]=[C:6]([CH:8]=[O:9])[CH:5]=[CH:4][CH:3]=1.[CH:10]1(CC(C2C=CC=CN=2)O)C[CH2:11]1>>[CH3:1][C:2]1[N:7]=[C:6]([CH:8]([OH:9])[CH2:10][CH3:11])[CH:5]=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 707376-Methyl-2-pyridinecarboxaldehyde

HCID 585730662-Cyclopropyl-1-(pyridin-2-yl)ethanol

생성물 1

HCID 211184631-(6-Methylpyridin-2-yl)propan-1-ol

실험 절차

The title compound was prepared from 6-methyl-2-pyridinecarboxaldehyde (purchased from Tokyo Chemical Industry Co. Ltd.) using a procedure similar to the one described above for the synthesis of 2-cyclopropyl-1-(pyridin-2-yl)ethanol (Example 232, Step A). Mass Spectrum (ESI) m/z=151.4 (M+1).

출처 및 근거

ORD 기록: ord-3c2bd1b1f0484c3db43faca1e6211a7b
출처 데이터셋: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09296736B2

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