Toluene → 5-(3-Chloro-2-fluorobenzyl)-2-fluoro-4-methoxybenzoyl chloride

반응식

[CH3:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1.[Cl:1][c:2]1[c:3]([F:21])[c:4]([CH2:5][c:6]2[c:7]([O:16][CH3:17])[cH:8][c:9]([F:15])[c:10]([C:11](=[O:12])[OH:13])[cH:14]2)[cH:18][cH:19][cH:20]1.[S:22]([Cl:23])([Cl:24])=[O:25]>>[Cl:1][c:2]1[c:3]([F:21])[c:4]([CH2:5][c:6]2[c:7]([O:16][CH3:17])[cH:8][c:9]([F:15])[c:10]([C:11](=[O:12])[Cl:24])[cH:14]2)[cH:18][cH:19][cH:20]1

참가 물질

반응물 3

HCID 1140Toluene

HCID 24386Thionyl Chloride

HCID 575728415-(3-Chloro-2-fluorobenzyl)-2-fluoro-4-methoxybenzoic acid

생성물 1

HCID 575728405-(3-Chloro-2-fluorobenzyl)-2-fluoro-4-methoxybenzoyl chloride

출처 및 근거

ORD 기록: ord-1c6584419e18451d8d38a9fdad3183e5
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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