4-Methylbicyclo[2.2.2]octan-1-amine → 4-Fluoro-1-[2-[(4-methyl-1-bicyclo[2.2.2]octanyl)amino]acetyl]pyrrolidine-2-carbonitrile

반응식

[Br:11][CH2:12][C:13](=[O:14])[N:15]1[CH:16]([C:21]#[N:22])[CH2:17][CH:18]([F:20])[CH2:19]1.[NH2:1][C:2]12[CH2:3][CH2:4][C:5]([CH3:10])([CH2:6][CH2:7]1)[CH2:8][CH2:9]2>>[NH:1]([C:2]12[CH2:3][CH2:4][C:5]([CH3:10])([CH2:6][CH2:7]1)[CH2:8][CH2:9]2)[CH2:12][C:13](=[O:14])[N:15]1[CH:16]([C:21]#[N:22])[CH2:17][CH:18]([F:20])[CH2:19]1

참가 물질

반응물 2

HCID 131846104-Methylbicyclo[2.2.2]octan-1-amine

HCID 231496951-(2-Bromoacetyl)-4-fluoropyrrolidine-2-carbonitrile

생성물 1

HCID 231529524-Fluoro-1-[2-[(4-methyl-1-bicyclo[2.2.2]octanyl)amino]acetyl]pyrrolidine-2-carbonitrile

출처 및 근거

ORD 기록: ord-674c0b2086b94d2497d3ca990af4e97c
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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