N-methyl-2-pyrrolidone → 1-tert-butyl-5-(3-hydroxy-pyrrolidin-1-yl)-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide

HRID 934181

반응식

HRID 934181 반응식
[CH3:30][N:31]1[CH2:32][CH2:33][CH2:34][C:35]1=[O:36].[CH:1]12[CH:2]([NH:11][C:12](=[O:13])[c:14]3[cH:15][n:16][n:17]([C:20]([CH3:21])([CH3:22])[CH3:23])[c:18]3[Cl:19])[CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2.[NH:24]1[CH2:25][CH:26]([OH:29])[CH2:27][CH2:28]1>>[CH:1]12[CH:2]([NH:11][C:12](=[O:13])[c:14]3[cH:15][n:16][n:17]([C:20]([CH3:21])([CH3:22])[CH3:23])[c:18]3[N:24]3[CH2:25][CH:26]([OH:29])[CH2:27][CH2:28]3)[CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2

참가 물질

4

반응물 3

HCID 13387N-methyl-2-pyrrolidoneHCID 982104-HydroxypyrrolidineHCID 250144171-tert-butyl-5-chloro-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide

생성물 1

HCID 250144181-tert-butyl-5-(3-hydroxy-pyrrolidin-1-yl)-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide

출처 및 근거

ORD 기록
ord-746afa6d01ae4449b73439ebb3131b1c
출처 데이터셋
Validation data from https://doi.org/10.1039/C8SC04228D

연결된 노트

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