2,2-dimethyl-N-[2-methyl-2-(4-nitro-1H-imidazol-1-yl)propyl]propan-1-amine → 2-[2-(3,5-Difluoro-phenyl)-acetylamino]-N-{1-[2-(2,2-dimethyl-propylamino)-1,1-dimethyl-ethyl]-1H-imidazol-4-yl}-2-(4-fluoro-phenyl)-acetamide

반응식

[CH3:1][C:2]([CH2:3][NH:4][CH2:5][C:6]([CH3:7])([CH3:8])[CH3:9])([CH3:10])[n:11]1[cH:12][n:13][c:14]([N+:16]([O-:17])=[O:18])[cH:15]1.[F:19][c:20]1[cH:21][c:22]([CH2:27][C:28](=[O:29])[NH:30][CH:31]([C:32](=[O:33])[OH:34])[c:35]2[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]2)[cH:23][c:24]([F:26])[cH:25]1>>[CH3:1][C:2]([CH2:3][NH:4][CH2:5][C:6]([CH3:7])([CH3:8])[CH3:9])([CH3:10])[n:11]1[cH:12][n:13][c:14]([NH:16][C:32]([CH:31]([NH:30][C:28]([CH2:27][c:22]2[cH:21][c:20]([F:19])[cH:25][c:24]([F:26])[cH:23]2)=[O:29])[c:35]2[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]2)=[O:33])[cH:15]1

참가 물질

반응물 2

HCID 671640862,2-dimethyl-N-[2-methyl-2-(4-nitro-1H-imidazol-1-yl)propyl]propan-1-amine

HCID 775029142-[[2-(3,5-Difluorophenyl)acetyl]amino]-2-(4-fluorophenyl)acetic acid

생성물 1

HCID 161136872-[2-(3,5-Difluoro-phenyl)-acetylamino]-N-{1-[2-(2,2-dimethyl-propylamino)-1,1-dimethyl-ethyl]-1H-imidazol-4-yl}-2-(4-fluoro-phenyl)-acetamide

출처 및 근거

ORD 기록: ord-82c5d470a9e64f629765be42015f1aff
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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