Tetrahydrofuran → N-[[3-[3-fluoro-4-(4-hydroxy-3,3,4-trimethylpiperidin-1-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

반응식

[CH3:28][Li:29].[O:1]=[C:2]1[C:3]([CH3:26])([CH3:27])[CH2:4][N:5]([c:8]2[c:9]([F:25])[cH:10][c:11]([N:14]3[C:15](=[O:24])[O:16][CH:17]([CH2:19][NH:20][C:21]([CH3:22])=[O:23])[CH2:18]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1.[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[OH:1][C:2]1([CH3:28])[C:3]([CH3:26])([CH3:27])[CH2:4][N:5]([c:8]2[c:9]([F:25])[cH:10][c:11]([N:14]3[C:15](=[O:24])[O:16][CH:17]([CH2:19][NH:20][C:21]([CH3:22])=[O:23])[CH2:18]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1

참가 물질

반응물 3

HCID 8028Tetrahydrofuran

HCID 68695641N-[[3-[4-(3,3-dimethyl-4-oxopiperidin-1-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

HCID 178418348HCID 178418348, 화합물

생성물 1

HCID 68698642N-[[3-[3-fluoro-4-(4-hydroxy-3,3,4-trimethylpiperidin-1-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

출처 및 근거

ORD 기록: ord-fe7d2867f20b457fb49bd37ed0a38150
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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