N2-(4-bromo-2-fluorophenyl)-1,3-benzothiazol-2-amine → N2-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3-benzothiazol-2-amine

반응식

[Br:1][c:2]1[cH:3][c:4]([F:18])[c:5]([NH:8][c:9]2[s:10][c:11]3[c:12]([n:13]2)[cH:14][cH:15][cH:16][cH:17]3)[cH:6][cH:7]1.[F:19][c:20]1[cH:21][c:22]([B:26]2[O:27][C:28]([CH3:33])([CH3:34])[C:29]([CH3:31])([CH3:32])[O:30]2)[cH:23][cH:24][c:25]1[NH:35][c:36]1[o:37][c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]2[n:44]1>>[c:2]1([B:26]2[O:27][C:28]([CH3:33])([CH3:34])[C:29]([CH3:31])([CH3:32])[O:30]2)[cH:3][c:4]([F:18])[c:5]([NH:8][c:9]2[s:10][c:11]3[c:12]([n:13]2)[cH:14][cH:15][cH:16][cH:17]3)[cH:6][cH:7]1

참가 물질

반응물 2

HCID 21985682N2-(4-bromo-2-fluorophenyl)-1,3-benzothiazol-2-amine

HCID 22347094N2-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3-benzoxazol-2-amine

생성물 1

HCID 22347070N2-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3-benzothiazol-2-amine

출처 및 근거

ORD 기록: ord-ae848c7833f5405380397def9f3cdb23
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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