Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium borohydride → 4-Bromo-3-chloro-3,4,4-trifluorobutan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | 4-Bromo-3-chloro-3,4,4-trifluorobutanal | HCID 21836480 | — |
| 생성물 | 4-Bromo-3-chloro-3,4,4-trifluorobutan-1-ol | HCID 21836477 | — |
반응 단계
Alternatively, the intermediate VII can be reduced with sodium borohydride without isolation to give 4-bromo-3-chloro-3,4,4-trifiuorobutanol ((IX) in high yield; or by hydrolysis of 1,4-dibromo-2-chloro-1,1,2-trifiuorobutane (XVI) to give IX. Oxidation of IX with Jones reagent to give VIII in 85% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05723470 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-4d3c86752d15461798923a512c8e5d21 |
| 출처 메모 | uspto-grants-1998_03 |