N-methyl-2-pyrrolidone → N'-(2-amino-7-(2-((2-((2,4-difluorophenyl)(methyl)amino)ethyl)(methyl)amino)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)furan-2-carbohydrazide

반응식

[CH3:37][N:38]1[CH2:39][CH2:40][CH2:41][C:42]1=[O:43].[NH2:1][c:2]1[n:3][c:4]([Cl:27])[c:5]2[c:6]([n:7]1)[n:8]([CH2:11][CH2:12][N:13]([CH2:14][CH2:15][N:16]([CH3:17])[c:18]1[c:19]([F:25])[cH:20][c:21]([F:24])[cH:22][cH:23]1)[CH3:26])[cH:9][cH:10]2.[o:28]1[c:29]([C:33](=[O:34])[NH:35][NH2:36])[cH:30][cH:31][cH:32]1>>[NH2:1][c:2]1[n:3][c:4]([NH:36][NH:35][C:33]([c:29]2[o:28][cH:32][cH:31][cH:30]2)=[O:34])[c:5]2[c:6]([n:7]1)[n:8]([CH2:11][CH2:12][N:13]([CH2:14][CH2:15][N:16]([CH3:17])[c:18]1[c:19]([F:25])[cH:20][c:21]([F:24])[cH:22][cH:23]1)[CH3:26])[cH:9][cH:10]2