Dichloromethane → 4-[2-(Trifluoromethyl)phenoxy]piperidine

HRID 94170

반응식

[Cl:32][CH2:33][Cl:34].[F:8][C:9]([c:10]1[c:11]([O:12][CH:13]2[CH2:14][CH2:15][N:16]([C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH2:17][CH2:18]2)[cH:26][cH:27][cH:28][cH:29]1)([F:30])[F:31].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[F:8][C:9]([c:10]1[c:11]([O:12][CH:13]2[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]2)[cH:26][cH:27][cH:28][cH:29]1)([F:30])[F:31]

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 46941590Tert-butyl 4-(2-(trifluoromethyl)phenoxy)piperidine-1-carboxylate

생성물 1

HCID 50187904-[2-(Trifluoromethyl)phenoxy]piperidine

출처 및 근거

ORD 기록: ord-140fa8e5c9c4455eb7d51ba53583d57e
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

연결된 노트

불러오는 중…