6-Chloro-2-methoxynicotinonitrile → 6-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino)ethyl)amino]-2-methoxypyridine-3-carbonitrile

HRID 941996노트

반응식

HRID 941996 반응식
[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[cH:6][cH:7][c:8]1-[c:9]1[c:10](-[n:11]2[cH:12][cH:13][n:14][cH:15]2)[cH:16][n:17][c:18]([CH2:19][CH2:20][NH2:21])[n:22]1.[Cl:23][c:24]1[cH:25][cH:26][c:27]([C:32]#[N:33])[c:28]([O:30][CH3:31])[n:29]1.[Cl:34][c:35]1[c:36](-[c:42]2[n:43][c:44]([NH:53][CH2:54][CH2:55][NH:56][c:57]3[cH:58][cH:59][c:60]([N+:61]([O-:62])=[O:63])[c:64]([O:65][CH3:66])[n:67]3)[n:45][cH:46][c:47]2-[c:48]2[nH:49][cH:50][cH:51][n:52]2)[cH:37][cH:38][c:39]([Cl:41])[cH:40]1>>[c:24]1([NH:56][CH2:55][CH2:54][NH:53][c:44]2[n:43][c:42](-[c:36]3[c:35]([Cl:34])[cH:40][c:39]([Cl:41])[cH:38][cH:37]3)[c:47](-[c:48]3[n:49][cH:50][cH:51][nH:52]3)[cH:46][n:45]2)[cH:25][cH:26][c:27]([C:32]#[N:33])[c:28]([O:30][CH3:31])[n:29]1

참가 물질

4

반응물 3

HCID 143811116-Chloro-2-methoxynicotinonitrileHCID 22142635[4-(2,4-Dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl)) amino]ethyl}amineHCID 571748954-(2,4-Dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-ylethylamine

생성물 1

HCID 221430106-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino)ethyl)amino]-2-methoxypyridine-3-carbonitrile

출처 및 근거

ORD 기록
ord-c6b8019eb8ef444084f6aefc84ef5c17
출처 데이터셋
Validation data from https://doi.org/10.1039/C8SC04228D

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