Piperidin-4-ol → 8-(1-(3,5-difluorophenyl)pyrrolidin-2-yl)-6-(4-hydroxypiperidine-1-carbonyl)-2-morpholino-4H-chromen-4-one

반응식

[F:1][c:2]1[cH:3][c:4]([N:9]2[CH:10]([c:14]3[cH:15][c:16]([C:31](=[O:32])[OH:33])[cH:17][c:18]4[c:19](=[O:30])[cH:20][c:21]([N:24]5[CH2:25][CH2:26][O:27][CH2:28][CH2:29]5)[o:22][c:23]34)[CH2:11][CH2:12][CH2:13]2)[cH:5][c:6]([F:8])[cH:7]1.[NH:34]1[CH2:35][CH2:36][CH:37]([OH:40])[CH2:38][CH2:39]1>>[F:1][c:2]1[cH:3][c:4]([N:9]2[CH:10]([c:14]3[cH:15][c:16]([C:31](=[O:32])[N:34]4[CH2:35][CH2:36][CH:37]([OH:40])[CH2:38][CH2:39]4)[cH:17][c:18]4[c:19](=[O:30])[cH:20][c:21]([N:24]5[CH2:25][CH2:26][O:27][CH2:28][CH2:29]5)[o:22][c:23]34)[CH2:11][CH2:12][CH2:13]2)[cH:5][c:6]([F:8])[cH:7]1

참가 물질

반응물 2

HCID 79341Piperidin-4-ol

HCID 866724028-(1-(3,5-difluorophenyl)pyrrolidin-2-yl)-2-morpholino-4-oxo-4H-chromene-6-carboxylic acid

생성물 1

HCID 866724088-(1-(3,5-difluorophenyl)pyrrolidin-2-yl)-6-(4-hydroxypiperidine-1-carbonyl)-2-morpholino-4H-chromen-4-one

출처 및 근거

ORD 기록: ord-adc260275471404297b4f415bdfc9e8f
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…