Acetonitrile → 7-[3-[(Ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-1-methylamino-4-oxo-3-quinolinecarboxylic acid

반응식

[CH2:20]([CH3:21])[NH:22][CH2:23][CH:24]1[CH2:25][NH:26][CH2:27][CH2:28]1.[CH3:29][C:30]#[N:31].[F:1][c:2]1[cH:3][c:4]2[c:5](=[O:19])[c:6]([C:16](=[O:17])[OH:18])[cH:7][n:8]([NH:14][CH3:15])[c:9]2[c:10]([F:13])[c:11]1[F:12]>>[F:1][c:2]1[cH:3][c:4]2[c:5](=[O:19])[c:6]([C:16](=[O:17])[OH:18])[cH:7][n:8]([NH:14][CH3:15])[c:9]2[c:10]([F:13])[c:11]1[N:26]1[CH2:25][CH:24]([CH2:23][NH:22][CH2:20][CH3:21])[CH2:28][CH2:27]1

참가 물질

반응물 3

HCID 6342Acetonitrile

HCID 13491786Ethyl-pyrrolidin-3-ylmethyl-amine

HCID 135580371-Methylamino-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

생성물 1

HCID 137119917-[3-[(Ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-1-methylamino-4-oxo-3-quinolinecarboxylic acid

출처 및 근거

ORD 기록: ord-e406a3137026422b89f0e4a732357558
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…