3,5-Bis-trifluoromethylphenylboronic acid → 5-(3,5-Di(trifluoromethyl)phenyl)-3-(1-Methylpiperidin-4-yl)-4-Aza-1H-Indole

반응식

[F:1][C:2]([F:3])([F:4])[S:5]([O:6][c:7]1[n:8][c:9]2[c:10]([CH:16]3[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]3)[cH:11][nH:12][c:13]2[cH:14][cH:15]1)(=[O:23])=[O:24].[F:25][C:26]([c:27]1[cH:28][c:29]([B:37]([OH:38])[OH:39])[cH:30][c:31]([C:33]([F:34])([F:35])[F:36])[cH:32]1)([F:40])[F:41]>>[c:7]1(-[c:29]2[cH:28][c:27]([C:26]([F:25])([F:40])[F:41])[cH:32][c:31]([C:33]([F:34])([F:35])[F:36])[cH:30]2)[n:8][c:9]2[c:10]([CH:16]3[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]3)[cH:11][nH:12][c:13]2[cH:14][cH:15]1

참가 물질

반응물 2

HCID 1562653,5-Bis-trifluoromethylphenylboronic acid

HCID 120418125-Trifluoromethanesulfonyloxy-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

생성물 1

HCID 98671915-(3,5-Di(trifluoromethyl)phenyl)-3-(1-Methylpiperidin-4-yl)-4-Aza-1H-Indole

출처 및 근거

ORD 기록: ord-db15971db615407480dead05a9b99489
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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