2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid → 1-(4-{2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoylamino}-imidazol-1-yl)-cyclobutanecarboxylic acid methyl ester

반응식

[CH3:1][O:2][C:3](=[O:4])[C:5]1([n:9]2[cH:10][n:11][c:12]([N+:14]([O-:15])=[O:16])[cH:13]2)[CH2:6][CH2:7][CH2:8]1.[F:17][c:18]1[cH:19][c:20]([CH2:25][C:26](=[O:27])[NH:28][CH:29]([C:30](=[O:31])[OH:32])[CH2:33][CH2:34][CH3:35])[cH:21][c:22]([F:24])[cH:23]1>>[CH3:1][O:2][C:3](=[O:4])[C:5]1([n:9]2[cH:10][n:11][c:12]([NH:14][C:30]([CH:29]([NH:28][C:26]([CH2:25][c:20]3[cH:19][c:18]([F:17])[cH:23][c:22]([F:24])[cH:21]3)=[O:27])[CH2:33][CH2:34][CH3:35])=[O:31])[cH:13]2)[CH2:6][CH2:7][CH2:8]1

참가 물질

반응물 2

HCID 219429862-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid

HCID 684659501-(4-Nitro-imidazol-1-yl)-cyclobutanecarboxylic acid methyl ester

생성물 1

HCID 684664521-(4-{2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoylamino}-imidazol-1-yl)-cyclobutanecarboxylic acid methyl ester

출처 및 근거

ORD 기록: ord-5595caeca53345f793904aefbb9fbcc1
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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