4-Bromo-2-cyanopyridine → 2'-Cyano-6-methyl-[4,4']bipyridinyl-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide

반응식

[Br:26][c:27]1[cH:28][c:29]([C:33]#[N:34])[n:30][cH:31][cH:32]1.[CH3:1][n:2]1[n:3][c:4]([NH:7][C:8](=[O:9])[c:10]2[n:11][c:12]([CH3:25])[cH:13][c:14]([B:16]3[O:17][C:18]([CH3:19])([CH3:20])[C:21]([CH3:22])([CH3:23])[O:24]3)[cH:15]2)[cH:5][cH:6]1>>[CH3:1][n:2]1[n:3][c:4]([NH:7][C:8](=[O:9])[c:10]2[n:11][c:12]([CH3:25])[cH:13][c:14](-[c:27]3[cH:28][c:29]([C:33]#[N:34])[n:30][cH:31][cH:32]3)[cH:15]2)[cH:5][cH:6]1

참가 물질

반응물 2

HCID 6932834-Bromo-2-cyanopyridine

HCID 671639792-Methyl-6-((1-methyl-1H-pyrazol-3-yl)carbamoyl)pyridine-4-boronic acid pinacol ester

생성물 1

HCID 248209762'-Cyano-6-methyl-[4,4']bipyridinyl-2-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide

출처 및 근거

ORD 기록: ord-4e71b7329772401197cccd256436edcc
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…