Dichloromethane → 4-[4-(9-Oxa-3,7-diazabicyclo[3.3.1]non-3-yl)butyl]benzonitrile

반응식

[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][CH2:11][CH2:12][N:13]2[CH2:14][CH:15]3[CH2:16][N:17]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:18][CH:19]([CH2:20]2)[O:21]3)[cH:7][cH:8]1.[Cl:36][CH2:37][Cl:38].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][CH2:11][CH2:12][N:13]2[CH2:14][CH:15]3[CH2:16][NH:17][CH2:18][CH:19]([CH2:20]2)[O:21]3)[cH:7][cH:8]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 18540378Tert-butyl 7-[4-(4-cyanophenyl)butyl]-9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate

생성물 1

HCID 179653304-[4-(9-Oxa-3,7-diazabicyclo[3.3.1]non-3-yl)butyl]benzonitrile

출처 및 근거

ORD 기록: ord-8775db8fb5d9411db4b554a6b9eb5df7
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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