5-(Trifluoromethyl)pyrazin-2-amine → 5-(Trifluoromethyl)-6-(8-(5-(trifluoromethyl)pyrazin-2-ylamino)pyrido[2,3-b]pyrazin-3-yl)nicotinamide

반응식

[Cl:1][c:2]1[cH:3][cH:4][n:5][c:6]2[n:7][c:8](-[c:12]3[n:13][cH:14][c:15]([C:16](=[O:17])[NH2:18])[cH:19][c:20]3[C:21]([F:22])([F:23])[F:24])[cH:9][n:10][c:11]12.[NH2:25][c:26]1[n:27][cH:28][c:29]([C:32]([F:33])([F:34])[F:35])[n:30][cH:31]1>>[c:2]1([NH:25][c:26]2[n:27][cH:28][c:29]([C:32]([F:33])([F:34])[F:35])[n:30][cH:31]2)[cH:3][cH:4][n:5][c:6]2[n:7][c:8](-[c:12]3[n:13][cH:14][c:15]([C:16](=[O:17])[NH2:18])[cH:19][c:20]3[C:21]([F:22])([F:23])[F:24])[cH:9][n:10][c:11]12

참가 물질

반응물 2

HCID 133411155-(Trifluoromethyl)pyrazin-2-amine

HCID 671914016-(8-Chloropyrido[2,3-b]pyrazin-3-yl)-5-(trifluoromethyl)nicotinamide

생성물 1

HCID 586457305-(Trifluoromethyl)-6-(8-(5-(trifluoromethyl)pyrazin-2-ylamino)pyrido[2,3-b]pyrazin-3-yl)nicotinamide

출처 및 근거

ORD 기록: ord-a73637f207794f89a1b6b4d199925b1d
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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