5-Bromo-1,2,3-trimethoxybenzene → 7-[(Tertbutyldimethylsilyl)oxy]-1-hydroxy-6-methoxy-1-(3',4',5'-trimethoxyphenyl)-tetralin

HRID 94453

반응식

HRID 94453 반응식
[C:19]([CH3:20])([CH3:21])([CH3:22])[Si:23]([O:24][c:25]1[c:26]([O:36][CH3:37])[cH:27][c:28]2[c:33]([cH:34]1)[C:32](=[O:35])[CH2:31][CH2:30][CH2:29]2)([CH3:38])[CH3:39].[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:6][O:7][c:8]1[cH:9][c:10]([Br:18])[cH:11][c:12]([O:16][CH3:17])[c:13]1[O:14][CH3:15]>>[CH3:6][O:7][c:8]1[cH:9][c:10]([C:32]2([OH:35])[CH2:31][CH2:30][CH2:29][c:28]3[cH:27][c:26]([O:36][CH3:37])[c:25]([O:24][Si:23]([C:19]([CH3:20])([CH3:21])[CH3:22])([CH3:38])[CH3:39])[cH:34][c:33]32)[cH:11][c:12]([O:16][CH3:17])[c:13]1[O:14][CH3:15]

참가 물질

4

반응물 3

HCID 758855-Bromo-1,2,3-trimethoxybenzeneHCID 222447927-[(tertButyldimethylsilyl)oxy]-6-methoxy-1-tetraloneHCID 178418339Butyllithium

생성물 1

HCID 181883597-[(Tertbutyldimethylsilyl)oxy]-1-hydroxy-6-methoxy-1-(3',4',5'-trimethoxyphenyl)-tetralin

출처 및 근거

ORD 기록
ord-46cdd9b45441415a8149e3e908ce97cc
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

연결된 노트

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