Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Aminomethyltetrahydropyran → (7-Bromo-3-nitroquinolin-4-yl)(tetrahydropyran-4-ylmethyl)amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Aminomethyltetrahydropyran | HCID 2773210 | — |
| 반응물 | 7-Bromo-4-chloro-3-nitroquinoline | HCID 21984361 | — |
| 생성물 | (7-Bromo-3-nitroquinolin-4-yl)(tetrahydropyran-4-ylmethyl)amine | HCID 21984259 | 94.3% |
반응 단계
The method described in Part E of Examples 431–436 was used to treat 7-bromo-4-chloro-3-nitroquinoline (12.43 g, 43.45 mmol) with C-(tetrahydropyran-4-yl)methylamine (10 g, 87 mmol) to provide 15.0 g of (7-bromo-3-nitroquinolin-4-yl)(tetrahydropyran-4-ylmethyl)amine as a bright yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07091214B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-f146f725e49749349a288d4b0e2fcd92 |
| 출처 메모 | uspto-grants-2006_08 |