3-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine → 4-Fluoro-1-(3-(5-fluoropyridin-3-yl)phenyl)-1-(pyridin-4-yl)-1H-isoindol-3-amine

반응식

[Br:1][c:2]1[cH:3][c:4]([C:8]2([c:19]3[cH:20][cH:21][n:22][cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1.[F:25][c:26]1[cH:27][n:28][cH:29][c:30]([B:32]2[O:33][C:34]([CH3:35])([CH3:36])[C:37]([CH3:38])([CH3:39])[O:40]2)[cH:31]1>>[c:2]1(-[c:30]2[cH:29][n:28][cH:27][c:26]([F:25])[cH:31]2)[cH:3][c:4]([C:8]2([c:19]3[cH:20][cH:21][n:22][cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:5][cH:6][cH:7]1

참가 물질

반응물 2

HCID 164142683-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

HCID 585794851-(3-bromophenyl)-4-fluoro-1-(pyridin-4-yl)-1H-isoindol-3-amine

생성물 1

HCID 462062944-Fluoro-1-(3-(5-fluoropyridin-3-yl)phenyl)-1-(pyridin-4-yl)-1H-isoindol-3-amine

출처 및 근거

ORD 기록: ord-4cd20cc0311c4c4ab4ab5f6de9e711f8
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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