Pyridine → 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-hydroxy-1-piperidinyl)-4-oxoquinoline-3-carboxylic acid

HRID 94852

반응식

[CH2:1]([CH3:2])[n:3]1[cH:4][c:5]([C:17](=[O:18])[OH:19])[c:6](=[O:16])[c:7]2[cH:8][c:9]([F:15])[c:10]([F:14])[c:11]([F:13])[c:12]12.[OH:20][CH:21]1[CH2:22][NH:23][CH2:24][CH2:25][CH2:26]1.[cH:27]1[cH:28][cH:29][n:30][cH:31][cH:32]1>>[CH2:1]([CH3:2])[n:3]1[cH:4][c:5]([C:17](=[O:18])[OH:19])[c:6](=[O:16])[c:7]2[cH:8][c:9]([F:15])[c:10]([N:23]3[CH2:22][CH:21]([OH:20])[CH2:26][CH2:25][CH2:24]3)[c:11]([F:13])[c:12]12

참가 물질

반응물 3

HCID 1049Pyridine

HCID 232933-Hydroxypiperidine

HCID 98351791-Ethyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

생성물 1

HCID 127709151-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-hydroxy-1-piperidinyl)-4-oxoquinoline-3-carboxylic acid

출처 및 근거

ORD 기록: ord-e54962279bff4370ba13afc4352009db
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

연결된 노트

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