Trifluoroacetic acid → 2-(4-(3-(5-(4-Bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoic acid

반응식

[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([C:13]([CH2:14][CH2:15][c:16]3[c:17]([Cl:34])[c:18]([Cl:33])[c:19]([O:20][C:21]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])([CH3:29])[CH3:30])[cH:31][cH:32]3)=[O:35])[s:12]2)[cH:6][cH:7]1.[OH:36][C:37]([C:38]([F:39])([F:40])[F:41])=[O:42]>>[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([C:13]([CH2:14][CH2:15][c:16]3[c:17]([Cl:34])[c:18]([Cl:33])[c:19]([O:20][C:21]([C:22](=[O:23])[OH:24])([CH3:29])[CH3:30])[cH:31][cH:32]3)=[O:35])[s:12]2)[cH:6][cH:7]1

참가 물질

반응물 2

HCID 6422Trifluoroacetic acid

HCID 25061023Tert-butyl 2-(4-(3-(5-(4-bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoate

생성물 1

HCID 250610242-(4-(3-(5-(4-Bromophenyl)thien-2-yl)-3-oxopropyl)-2,3-dichlorophenoxy)-2-methylpropanoic acid

출처 및 근거

ORD 기록: ord-349767b16ddb4ee9b9748149dd14d951
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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