Dichloromethane → 4-phenethyl-2-(6-(1H-pyrrol-1-yl)pyridine-3-carboxamido)benzoic acid

반응식

[CH2:43]([Cl:44])[Cl:45].[CH2:8]([CH2:9][c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1)[c:16]1[cH:17][c:18]([NH:29][C:30](=[O:31])[c:32]2[cH:33][n:34][c:35](-[n:38]3[cH:39][cH:40][cH:41][cH:42]3)[cH:36][cH:37]2)[c:19]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[cH:27][cH:28]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[CH2:8]([CH2:9][c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1)[c:16]1[cH:17][c:18]([NH:29][C:30](=[O:31])[c:32]2[cH:33][n:34][c:35](-[n:38]3[cH:39][cH:40][cH:41][cH:42]3)[cH:36][cH:37]2)[c:19]([C:20](=[O:21])[OH:22])[cH:27][cH:28]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 67342233tert-butyl 4-phenethyl-2-(6-(1H-pyrrol-1-yl)pyridine-3-carboxamido)benzoate

생성물 1

HCID 578793034-phenethyl-2-(6-(1H-pyrrol-1-yl)pyridine-3-carboxamido)benzoic acid

출처 및 근거

ORD 기록: ord-f9ef0d129b6a457aa6c118509e930b18
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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