Cisapride (USP/INN) → 4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-hydroxybenzamide

반응식

[CH3:1][CH2:2][N:3]([CH2:4][CH2:5][NH:6][C:7]([c:8]1[c:9]([O:10][CH3:11])[cH:12][c:13]([NH2:14])[c:15]([Cl:16])[cH:17]1)=[O:18])[CH2:19][CH3:20].[CH3:53][CH:54]([OH:55])[CH3:56].[NH2:21][c:22]1[cH:23][c:24]([O:51][CH3:52])[c:25]([C:26](=[O:27])[NH:28][CH:29]2[CH:30]([O:46][CH3:47])[CH2:31][N:32]([CH2:35][CH2:36][CH2:37][O:38][c:39]3[cH:40][cH:41][c:42]([F:45])[cH:43][cH:44]3)[CH2:33][CH2:34]2)[cH:48][c:49]1[Cl:50]>>[NH2:21][c:22]1[cH:23][c:24]([OH:51])[c:25]([C:26](=[O:27])[NH:28][CH:29]2[CH:30]([O:46][CH3:47])[CH2:31][N:32]([CH2:35][CH2:36][CH2:37][O:38][c:39]3[cH:40][cH:41][c:42]([F:45])[cH:43][cH:44]3)[CH2:33][CH2:34]2)[cH:48][c:49]1[Cl:50]

참가 물질

반응물 3

HCID 2769Cisapride (USP/INN)

HCID 3776Isopropanol

HCID 4168Metoclopramide

생성물 1

HCID 143725904-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-hydroxybenzamide

출처 및 근거

ORD 기록: ord-e894793a3c604984864e1cb58adbcf2b
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…