N-[3-(3-{2-[(3-Chloro-4-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}pyrazolo[1,5-a]pyridin-2-yl)phenyl]-2,6-difluorobenzamide → 3-Fluoro-4-(2-methoxyethoxy)aniline

반응식

[Cl:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[n:7][c:8](-[c:9]3[c:10](-[c:11]4[cH:12][c:13]([NH:14][C:15](=[O:16])[c:17]5[c:18]([F:19])[cH:20][cH:21][cH:22][c:23]5[F:24])[cH:25][cH:26][cH:27]4)[n:28][n:29]4[cH:30][cH:31][cH:32][cH:33][c:34]34)[cH:35][cH:36][n:37]2)[cH:38][cH:39][c:40]1[O:41][CH2:42][CH2:43][N:44]([CH3:45])[CH3:46].[F:47][c:48]1[c:49]([O:57][CH2:58][CH2:59][O:60][CH3:61])[cH:50][cH:51][c:52]([N+:54]([O-:55])=[O:56])[cH:53]1>>[F:47][c:48]1[c:49]([O:57][CH2:58][CH2:59][O:60][CH3:61])[cH:50][cH:51][c:52]([NH2:54])[cH:53]1

참가 물질

반응물 2

HCID 11505567N-[3-(3-{2-[(3-Chloro-4-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}pyrazolo[1,5-a]pyridin-2-yl)phenyl]-2,6-difluorobenzamide

HCID 234980752-Fluoro-1-(2-methoxyethoxy)-4-nitrobenzene

생성물 1

HCID 234981173-Fluoro-4-(2-methoxyethoxy)aniline

출처 및 근거

ORD 기록: ord-3d045df41bd44768bf75554461d48f2c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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