5-Methyl-1,3-thiazole-2-carboxylic acid → N-[1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]-5-methyl-1,3-thiazole-2-carboxamide

반응식

[CH3:30][c:31]1[cH:32][n:33][c:34]([C:36](=[O:37])[OH:38])[s:35]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]3[cH:12][c:13]([O:17][CH:18]([CH:19]([CH3:20])[NH2:21])[c:22]4[cH:23][c:24]([O:28][CH3:29])[cH:25][cH:26][cH:27]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]3[cH:12][c:13]([O:17][CH:18]([CH:19]([CH3:20])[NH:21][C:36]([c:34]4[n:33][cH:32][c:31]([CH3:30])[s:35]4)=[O:37])[c:22]4[cH:23][c:24]([O:28][CH3:29])[cH:25][cH:26][cH:27]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1

참가 물질

반응물 2

HCID 218773495-Methyl-1,3-thiazole-2-carboxylic acid

HCID 690532851-[1-(4-Fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-amine

생성물 1

HCID 72258630N-[1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]-5-methyl-1,3-thiazole-2-carboxamide

출처 및 근거

ORD 기록: ord-6fc66bba62a3414483d1fab4f6480cc1
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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