Dichloromethane → 7-chloro-3-(piperidin-4-yl)-1H-indole

반응식

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][nH:16][c:17]3[c:18]([Cl:23])[cH:19][cH:20][cH:21][c:22]23)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:31][CH2:32][Cl:33].[F:24][C:25]([F:26])([F:27])[C:28]([OH:29])=[O:30]>>[NH:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][nH:16][c:17]3[c:18]([Cl:23])[cH:19][cH:20][cH:21][c:22]23)[CH2:12][CH2:13]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 120720357-chloro-3-(1-tert-butoxycarbonylpiperidin-4-yl)-1H-indole

생성물 1

HCID 120720367-chloro-3-(piperidin-4-yl)-1H-indole

출처 및 근거

ORD 기록: ord-3cd13542fcbb4e8d9119fbbf286776f3
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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