Methanol → tert-Butyl 4-((5-amino-2-methoxybenzyloxy)methyl)-4-phenylpiperidine-1-carboxylate

반응식

[CH3:1][O:2][c:3]1[c:4]([CH2:5][O:6][CH2:7][C:8]2([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:27][c:28]([N+:31]([O-:32])=[O:33])[cH:29][cH:30]1.[CH3:34][OH:35].[Pd:36]>>[CH3:1][O:2][c:3]1[c:4]([CH2:5][O:6][CH2:7][C:8]2([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:27][c:28]([NH2:31])[cH:29][cH:30]1

참가 물질

반응물 3

HCID 887Methanol

HCID 23938Palladium

HCID 58993459tert-Butyl 4-((2-methoxy-5-nitrobenzyloxy)methyl)-4-phenylpiperidine-1-carboxylate

생성물 1

HCID 58993700tert-Butyl 4-((5-amino-2-methoxybenzyloxy)methyl)-4-phenylpiperidine-1-carboxylate

출처 및 근거

ORD 기록: ord-77850cecf0404d448b951f36d7b08e51
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…